
Excluding the Rinnegan Rikudo Sennin, there was only one and a half pairs of Rinnegan in the Shinobi World, canonically.
And in Rinnegan's one-and-a-half pair, Rinnegan Uchiha Sasuke also evolved because Rikudo Sennin gave him the Yin part of his own Chakrana, so on the one hand, it was not awakened by Sasuke himself, either, instead it was given to him by Rikudo Sennin to prevent Kaguya's awakening, so it cannot be used as a reference object by Kuroto, as this method is very difficult to replicate.
Thus, Madara's Uchiha method of awakening the Rinnegan is worth researching by Kuroto.
Rinnegan Uchiha Madara is a product of the fusion of the Yin Chakra of the Eternal Mangekyou Sharingan, and the Yang Chakra of the Hashirama Cell implanted in his body.
In other words, if we use the Rinnegan Madara as an example, the fusion of the Yin Chakra of the Eternal Mangekyou Sharingan and the Yang Chakra of the Hashirama Cell could theoretically result in the birth of the Rinnegan.
In addition, in the canon, Orochimaru and Yakushi Kabuto hypothesized that the Rinnegan could be awakened by combining Uchiha and Senju DNA. To that end, Kabuto managed to recreate the Rinnegan by implanting Hashirama Cells in Madara's reincarnated body.
But given that Uchiha Madara is the reincarnation of Otsutsuki Indra, at the same time, Senju Hashirama is the reincarnation of Otsutsuki Asura, so after implanting the Hashirama Cell, the, Madara has access to the Indra and Asura Chakras, and the combination of the Indra and Asura Chakras allows him to gain Hagoromo's own chakra so he awakens the Rinnegan.
If we recall both allegations, then the question arises here, whether combining the Indra and Asura Chakras to give birth to the Hagoromo Chakra is necessary or not to develop a pair of Rinnegan? Kuroto's goal is to solve this problem using this Implantation Surgery.
Kuroto wanted to understand whether Acquiring the Hagoromo Chakra was the only condition to awaken the Rinnegan or just one of many ways.
If Hagoromo's Chakra is not the only necessary condition, then Kuroto has the confidence in cultivating a pair of Rinnegan.
But if the Hagoromo Chakra is the only necessary condition, then Kuroto must involve Sasuke Uchiha as well in his research because Sasuke is the reincarnation of Indra.
With the aim of finding out the matter, Kuroto begins Operation Shisui implantation.
After installing all the devices to continuously monitor Shisui's vital signs the entire time, Kuroto disinfected the surgical instruments, then calmly replaced Shisui's eyes with Eternal Mangekyou's.
A few seconds after the eye was implanted in Shisui's cavity, Kuroto asked, "How do you feel?"
After adjusting to the returning vision, Shisui scanned the surroundings for a while, then said in a doubtful tone, “I'm not sure why, but these eyes gave me a very familiar sensation, and there is no resistance, as if these are no foreign body parts, rather they have become part of my body.”
Kuroto nodded with a smile after hearing Shisui's hesitation, "Good then."
The Mangekyou Eternal Sharingan Uchiha Ryota has been washed and maintained by the Tsukihi Clone Chakra for several years and has a high acceptance of the Tsukihi Clone Chakra.
The Tsukihi clone is a fusion of the Kuroto Cell and Shisui Cells, the sex of the resulting clone may have changed as the female gender-determining genes became dominant, but this does not change the fact that the Tsukihi Chakra Clone is very similar to the Chakra of Shisui himself., therefore it is only natural that this eye has a high acceptance rate of Shisui Chakra.
While Shisui was getting familiar with the Eternal Mangekyou Sharingan, Kuroto monitored the slight changes to his vital signs, and said, "Cell Activator in full effect, the activity of the cells in your body has increased by 17%, which is why it is so important that you can see that%, and it's still on the rise that's possible because of these eye implants. Activate the Eternal Mangekyou Sharingan and let the Yin Chakra flow in your brain.”
Shisui nodded, closed his eyelids, then opened them, and this time, the black eyes in his sockets had turned into the Eternal Mangekyou Sharingan.
Seeing that Shisui was able to activate those eyes perfectly, Kuroto nodded.
The first step of the operation is the replacement of the eye, which has been completed successfully, now arrives the next step to inject the Fusion Solution.
Fusion solutions are very unstable in nature, they can only remain stable for about an hour, after which they begin to decompose, and the decomposition reaction they generally follow is the zero order reaction, the, with a half-life period of 5 minutes.
As such, they cannot be stored in warehouses and must be prepared on sight.
So, Kuroto started the development of Fusion Solutions directly.
Since all the materials needed were already prepared in advance, so, it only took about half an hour for Kuroto to prepare the Fusion Solution. After being prepared, Kuroto moved the Fusion Solution into the injector, and carried the Kuroto injector walking towards the Operating Table.
After reading Shisui's Vital Signs, especially his Cell Activity and Body Temperature, Kuroto said, “Now I will inject Fusion Solution, be prepared to feel the pain.”
Shisui nodded calmly.
Kuroto then injects the drug's green color Fusion Solution into the Shisui Blood Flow.
Immediately after, the Fusion Solution was injected into Shisui's bloodstream, all of his veins bulged out, and the dark green-colored veins were now visible to the naked eye, it was as if something started to ferment in his body and the rate of transpiration increased again by 30%.
If it wasn't for the water droplets stuck to Shisui's arteries, he might have already died of dehydration.
Furthermore, his heart rate increased to 240 beats per minute which was already past dangerous levels even for top athletes, but he was a Shinobi, and Shinobi had to endure and so did Shisui. Intense pain raged on his body, it felt as if all of his veins were about to burst but Shisui simply gritted his teeth and endured the searing pain.
From the small fridge, Kuroto took out two injectors along with a dozen small glass capsules filled with whitish liquid.
The whitish liquid inside the glass capsule is a specially treated Hashirama Cell.
After putting the injector and the glass capsule on the side bench, Kuroto said to Shisui, “Effect Fusion Solution will only last for a short while, so the Cell Implantation should be done immediately, are you ready to face one of the most intense? suffering for the rest of your life?”
Shisui chuckled with a breath of breath, "Kuroto-san, you really aren't cheering up here."
“You're right, I guess.” Kuroto nodded, then said, "Okay, so what about this?"
'Jutsu Transformation!'
Poof!
Instantly, Kuroto turned into a cute and sexy nurse with big breasts, and said to Shisui in a cheering tone as she winked her left eye, "Ganbatte Kudasai Shisui-kun!"
“Coughs, it's not funny Kuroto-san!” Shisui coughed in embarrassment, she was speechless.
Kuroto chuckled then let go of her transformation, and asked, "Are you ready Shisui?" only this time, his tone was much more serious.
Shisui nodded, "Yes, right."
"Okay, so now I'm injecting Hashirama's cell." With that said, Kuroto placed the capsule on her injector, then after reading all the Shisui Vital Signs, she started injecting Hashirama Cells, and while watching the monitor, she said, “Don't forget to use Visual Prowess.to suppress Hashirama Cells take over your body, will power alone can't stop Hashirama Cell erosion.”
One by one, Kuroto began injecting 12 capsules into Shisui's body. The reason for more than one capsule is because it has reduced the potency of Hashirama Cells quite a lot, at the same time, each capsule contains a Solution that focuses on a particular gene, therefore, it is, all 12 are required for perfect implantation.
Kuroto determined this separation after studying Hashirama Cells with respect to his own genes and reaching the conclusion that for perfect implantation this method is currently the most suitable.
With impeccable implantation, Kuroto means no visible facial enhancement or whiteness on the body, which is different from Hashirama Madara, Obito, and Danzo Cell Implantation.
In Kuroto's view, their method is quite crude, so the results are not perfect, clearly visible traces of Hashirama cell implantation. Shodaime-sama's face is on Madara's Chest, on Danzo's shoulder, and on half of Obito's White Zetsu-type body.
Their implantation method is quite crude and only works at the cellular level, or organ level, whereas, Operation implantation, Kuroto's pursuit is at the Genetic Level, only when the genes themselves are altered, and so on, implantation surgery will work, this is his opinion.
In the current Shinobi World, there were very few people capable of reaching such a level, currently, they only included him, Orochimaru, and Hiruko, at the very least, as per Kuroto's understanding.
There may be some others, but Kuroto has yet to notice.
By the time the 12th Capsule was injected, Shisui was already writhing in pain, and this time the pain was so intense that even if he wanted to, he couldn't help but scream and wail, “Argghhhh.
'Jutsu Clone Multi Shadow!'
Poof Poof Poof Poof Poof
"Hold him!" Kuroto creates five Shadow Clones to keep Shisui in the operating bed, as well as inserts a piece of cloth into Shisui's mouth to ensure that he accidentally bites his tongue.
After injecting the 12th Capsule completely, Kuroto placed the Injector on the side and observed Shisui's state with his Tenseigan.
He could see, the intense increase in cellular activity was more than an additional 200% of the previous increase.
Shisui was struggling, and it took all five of Kuroto's clones to keep Shisui's body in bed.
If it is said that Kuroto himself is not nervous, then it is a lie. Several things in the Shinobi World could make him nervous, and Shisui's current state was one of them, too, even Kuroto could see some tree buds growing from Shisui's body and becoming a sapling if the bud continued to grow, then it would be very dangerous for Shisui.
But Kuroto could only look and wait and let Shisui fight out, 'Come on Shisui, I know you can do this.'
.
.